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Condition: Diabetes Mellitus

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Prevalence of Diabetes Mellitus in U.S. Youth in 2009: The SEARCH for Diabetes in Youth Study.
ConclusionDiabetes mellitus, one of the leading chronic diseases in childhood, affects over 190,000 (1 out of 433) youth less than age 20 years in the US, with racial and ethnic disparities seen in diabetes prevalence, overall and by diabetes type. PMID: 24041677 [PubMed - as supplied by publisher]
Source: Diabetes Care - September 16, 2013 Category: Endocrinology Authors: Pettitt DJ, Talton J, Dabelea D, Divers J, Imperatore G, Lawrence JM, Liese AD, Linder B, Mayer-Davis EJ, Pihoker C, Saydah SH, Standiford DA, Hamman RF, for the SEARCH for Diabetes in Youth Study Group Tags: Diabetes Care Source Type: research

Translating search strategies (updated)
This is an update of a post from November 2015.If you are doing a systematic review, you will need to run the same search in more than one database.I use the term " translation " for the process of modifying a search so that it works in another database.It is important to run the same search in all databases.So, if you have a search that works in Ovid Medline, what do you need to change to make it work in another database like PsycINFO or Embase?  Those other databases have different features or functionality.There are three areas where translation is necessary, once you have finalised your strategy:Search syntax – ...
Source: Browsing - August 22, 2017 Category: Databases & Libraries Source Type: blogs

Try the new Cochrane PICO search BETA on the Cochrane Library
Cochrane is excited to announce the beta release of a powerful and easy-to-use new discovery tool for finding reviews on theCochrane Library.Released to coincide with the Santiago Cochrane Colloquium, Cochrane PICO search BETA can help you find the most relevant Cochrane evidence to answer your research or clinical question.What is the Cochrane PICO search BETA?With Cochrane PICO search BETA, you can search over 4,500 Cochrane intervention reviews published since 2015 byPopulation (or Patient or Problem)What are the characteristics of the patient or population – for example condition? Intervention What is the interventi...
Source: Cochrane News and Events - October 15, 2019 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Translating search strategies
Not sure if I borrowed this term, or invented it, but I mean modifying a search strategy for use in another database.   For example, if you have a Medline strategy, what do you need to change to make it work in, say, PsycINFO or Embase?  Other databases might have different features or functionality.There are two areas where translation is necessary, once you have finalised your strategy.  I have assumed in what follows that you have a Medline strategy, and want to translate it for use in other databases.One area is search syntax (proximity operators, truncation, and so on), and the other is subject hea...
Source: Browsing - March 22, 2015 Category: Databases & Libraries Tags: literature searching Source Type: blogs

Electromagnetic Interference From Electronic Devices Used in the Management of Type 1 Diabetes Can Impair the Performance of an Avalanche Transceiver in Search Mode
Conclusions Electromagnetic interference produced by some diabetes devices when held within 30 cm of a searching avalanche transceiver can impair the ability to locate a signal. Such interference could significantly compromise the outcome of a companion rescue scenario. Further investigation using other pumps and rtCGMS devices is required to evaluate all available diabetes electronics. Meantime, all electronic diabetes devices including rtCGMS and insulin pumps should not be used within 30 cm of an avalanche transceiver.
Source: Wilderness and Environmental Medicine - March 13, 2015 Category: Environmental Health Source Type: research

The search for predictive metabolic biomarkers for incident T2DM
The search for predictive metabolic biomarkers for incident T2DM, Published online: 18 June 2018; doi:10.1038/s41574-018-0045-xA recent metabolomics study of plasma samples from normoglycaemic individuals has identified new predictive biomarkers for type 2 diabetes mellitus. The biomarkers described by the authors demonstrate a potential causal connection between changes in glycine and phenylalanine and incident diabetes mellitus.
Source: Nature Reviews Endocrinology - June 18, 2018 Category: Endocrinology Authors: Ewan Pearson Jerzy Adamski Source Type: research

Transition From Pediatric to Adult Care for Youth Diagnosed With Type 1 Diabetes in Adolescence
CONCLUSIONS: Transferring from pediatric to adult care, experienced by more than half the sample, was associated with an increased risk of poor glycemic control at follow-up. These findings suggest that young adults need additional support when moving to adult care.
Source: PEDIATRICS - April 1, 2013 Category: Pediatrics Authors: Lotstein, D. S., Seid, M., Klingensmith, G., Case, D., Lawrence, J. M., Pihoker, C., Dabelea, D., Mayer-Davis, E. J., Gilliam, L. K., Corathers, S., Imperatore, G., Dolan, L., Anderson, A., Bell, R. A., Waitzfelder, B., for the SEARCH for Diabetes in Yout Tags: Endocrinology Article Source Type: research

Idiopathic small fiber neuropathy: phenotype, etiologies, and the search for fabry disease.
CONCLUSIONS: A focused investigation may aid in uncovering further etiological factors in patients with seemingly idiopathic SFN, such as impaired glucose tolerance. However, idiopathic SFN in young to middle-aged Swedish patients does not seem to be due to late-onset Fabry disease. PMID: 24829596 [PubMed]
Source: Journal of Clinical Neurology - December 2, 2014 Category: Neurology Tags: J Clin Neurol Source Type: research

Electromagnetic interference from electronic devices used in the management of type 1 diabetes can impair the performance of an avalanche transceiver in search mode - Miller SC.
OBJECTIVE: Portable electronic devices play an important role in the management of type 1 diabetes mellitus. Electromagnetic interference from electronic devices has been shown to impair the function of an avalanche transceiver in search mode (but not in t...
Source: SafetyLit: All (Unduplicated) - March 26, 2015 Category: Global & Universal Tags: Environmental Issues, Climate, Geophysics Source Type: news

Type 1 diabetes, cognition and the neurologist: Exploring Go/No-Go and Maze tasks in the search for a practical screening tool.
CONCLUSIONS: We found indicators of inattention and impulsivity to be associated with T1DM, with inattention being closely related with hyperglycemia, and impulsivity being associated with hypoglycemia. Further research is needed to study diabetes-associated cognitive decline with more objective parameters, and to analyse the reliability and psychometric properties of the tasks proposed in this study. PMID: 28238464 [PubMed - as supplied by publisher]
Source: International Journal of Developmental Neuroscience - February 22, 2017 Category: Neuroscience Authors: Shinosaki JS, Rossini JC, Jorge ML, Macedo LB, Tannús PJ Tags: Int J Dev Neurosci Source Type: research

Use of new technologies by adolescents in the search for health information.
CONCLUSIONS: Adolescents seek information mainly through Google, with no knowledge of systems that accredit content quality, but consider it useful and reliable, changing their behaviour patterns according to the information found. All this carries a risk in this age group with very sensitive characteristics. Therefore, we believe that we should continue along the line of designing other alternative communication channels adapted to their current reality. PMID: 29426583 [PubMed - as supplied by publisher]
Source: Atencion Primaria - February 6, 2018 Category: Primary Care Authors: Blázquez Barba M, Gómez Romero D, Frontaura Fernández I, Camacho Ojeda A, Rodríguez Salas FM, Toriz Cano H Tags: Aten Primaria Source Type: research

An investigation on 4-thiazolidinone derivatives as dual inhibitors of aldose reductase and protein tyrosine phosphatase 1B, in the search for potential agents for the treatment of type 2 diabetes mellitus and its complications.
Abstract Designed multiple ligands (DMLs), developed to modulate simultaneously a number of selected targets involved in etiopathogenetic mechanisms of a multifactorial disease, such as diabetes mellitus (DM), are considered a promising alternative to combinations of drugs, when monotherapy results to be unsatisfactory. In this work, compounds 1-17 were synthesized and in vitro evaluated as DMLs directed to aldose reductase (AR) and protein tyrosine phosphatase 1B (PTP1B), two key enzymes involved in different events which are critical for the onset and progression of type 2 DM and related pathologies. Out of the ...
Source: Bioorganic and Medicinal Chemistry Letters - October 15, 2018 Category: Chemistry Authors: Maccari R, Del Corso A, Paoli P, Adornato I, Lori G, Balestri F, Cappiello M, Naß A, Wolber G, Ottanà R Tags: Bioorg Med Chem Lett Source Type: research

Phytomedicines Used for Diabetes Mellitus in Ghana: A Systematic Search and Review of Preclinical and Clinical Evidence.
Conclusion: This review contains information on medicinal plants used to manage diabetes mellitus, including their pharmacological properties and mechanisms of action as well as models used to investigate them. It also provides gaps that can form the basis for further investigations and development into useful medications for effective treatment of diabetes mellitus. PMID: 31118963 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - May 25, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Application of a Tabu search-based Bayesian network in identifying factors related to hypertension
The study aimed to study the related factors of hypertension using multivariate logistic regression analysis and tabu search-based Bayesian Networks (BNs). A cluster random sampling method was adopted to obtain samples of the general population aged 15 years or above. Multivariate logistic regression analysis indicated that gender, age, cultural level, body mass index (BMI), central obesity, drinking, diabetes mellitus, Myocardial infarction, Coronary heart disease, Stroke are associated with hypertension. While BNs found connections between those related factors and hypertension were established by complex network structu...
Source: Medicine - June 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Diabetes Mellitus in Children with Acute Recurrent and Chronic Pancreatitis: Data From the INternational Study Group of Pediatric Pancreatitis: In Search for a CuRE Cohort
Conclusion: Pancreatic atrophy may be more common among children with DM, suggesting more advanced exocrine disease. However, data in this exploratory cohort also suggest increased autoimmunity and hypertriglyceridemia in children with DM, suggesting that risk factors for type 1 and type 2 DM, respectively may play a role in mediating DM development in children with pancreatitis.
Source: Journal of Pediatric Gastroenterology and Nutrition - October 25, 2019 Category: Gastroenterology Tags: Original Article: Pancreatology Source Type: research